Ac-YVAD-2,6- dimethylbenzo yloxymethylket one
Catalog No:CP-CASP-008A
Manufacturer:CPC Scientific
Size:1 mg
CAS No.:[154674-81-4]
Formula:C33H42N 4O10
MWt:655
€59,00
Product Name: | Ac-YVAD-2,6- dimethylbenzo yloxymethylket one |
Category: | Peptides |
Three letter sequence: | Ac-Tyr-Val- Ala-Asp-2,6- dimethylbenz oyloxymethyl ketone |
One letter sequence: | Ac-YVAD-2,6- diMhylbenzoylox yMhylketone |
Description: | Highly selective, competitive and irreversible inhibitor of caspase-1 (ICE). Inactivation of the enzyme occurs with a rate limited by diffusion and is relatively inert toward other bionucleophiles such as glutathione, thus making it an excellent candidate for in vivo studies of enzyme inhibitors. |
Literature References: | N.A. Thornberry et al., Biochemistry , 33, 3934 (1994) |
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