Ac-WEHD- CHO
Catalog No:CP-CASP-004A
Manufacturer:CPC Scientific
Size:1 mg
CAS No.:[189275-71-6]
Formula:C28H33N 7O9
MWt:612
€30,00
Product Name: | Ac-WEHD- CHO |
Category: | Peptides |
Three letter sequence: | Ac-Trp-Glu- His-Asp-CHO |
One letter sequence: | Ac-WEHD-CHO |
Description: | Very potent reversible inhibitor of caspase-1 (ICE) that contains the optimal tetrapeptide recognition motif for this enzyme. With a Ki of 56 pM, it displays the most potent reversible, peptide-based inhibitors described for any protease. For caspase-8 a Ki of 21.1 nM has been reported. |
Literature References: | T.A. Rano et al., Chem. Biol ., 4, 149 (1997); M. Garcia-Calvo et al., J. Bio. Chem ., 273, 32608 (1998) |
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