(Ac-Nle4, Asp5, DPhe7, Lys10)-Cyclo- a-MSH (4-10) amide, MTII
Catalog No:CP-SOMA-003B
Manufacturer:CPC Scientific
Size:2 mg
Formula:C50H69N 15O9
MWt:1,024
€113,00
Product Name: | (Ac-Nle4, Asp5, DPhe7, Lys10)-Cyclo- a-MSH (4-10) amide, MTII |
Category: | Peptides |
Three letter sequence: | Ac-Nle- cyclo(Asp- His-DPhe- Arg-Trp-Lys- NH2)Peptide beta bond Asp3&Lys8 bridge |
One letter sequence: | Ac-Nle- cyclo(DHfRWK- NH2)Peptide beta bond D3&K8 bridge |
Description: | Cyclic MSH analog that is a potent full agonist of the melanocortin-3 and melanocortin-4 receptors (MC3-R and MC4-R). MTII is a useful tool in the study of the agouti obesity syndrome and the role of melanocortinergic neurons in feeding. |
Literature References: | V.J. Hruby et al., J. Med. Chem ., 38, 3435 (1995) |
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