Mast Cell Degranulating Peptide
Catalog No:CP-MCDP-003B
Manufacturer:CPC Scientific
Size:1 mg
Formula:C110H192 N40O24S 4
MWt:2,587
€196,00
Product Name: | Mast Cell Degranulating Peptide |
Category: | Peptides |
Three letter sequence: | Ile-Lys-Cys- Asn-Cys-Lys- Arg-His-Val- Ile-Lys-Pro- His-Ile-Cys- Arg-Lys-Ile- Cys-Gly-Lys- Asn- NH2(Cys3&C ys15 bridge , Cys5&Cys19 bridge) |
One letter sequence: | IKCNCKRHVIKP HICRKICGKN- NH2 (C3&C15 bridge , C5&C19 bridge) |
Description: | Highly basic MCD peptide is isolated from the venom of European honeybee, Apis Mellifera. At low doses, it leads to mast cell degranulation and subsequence histamine release. At higher doses, it causes an anti- inflammatory effect, beneficial in rheumatic and allergic diseases. |
Literature References: | M.E.J. Billingham et al., Nature, 245, 163 (1973) |
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