Western blot analysis of extracts of various cell lines, using HSPB8/HSP22 Rabbit mAb (A13518) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 3min.
HSPB8/HSP22 Rabbit mAb
Catalog No:AB-A13518
Manufacturer:ABclonal
Synonyms:CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | HSPB8/HSP22 Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008] |
Immunogen: | A synthesized peptide derived from human HSPB8/HSP22 |
Gene ID: | 26353 |
Swiss prot: | Q9UJY1 |
Molecular weight: | 22kDa |
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