ALAS1 Rabbit pAb
Catalog No:AB-A13462
Manufacturer:ABclonal
Synonyms:ALAS1;ALAS;ALAS-H;ALAS3;ALASH;MIG4
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | ALAS1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ALAS1 (NP_954635.1). |
Gene ID: | 211 |
Swiss prot: | P13196 |
Molecular weight: | 12kDa/70kDa |
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