.jpg)
Western blot analysis of extracts of various cell lines, using MLKL antibody (A13451) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
.jpg)
Western blot analysis of extracts of Mouse liver, using MLKL antibody (A13451) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
.jpg)
Western blot analysis of extracts of Rat testis, using MLKL antibody (A13451) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
.jpg)
Western blot analysis of extracts from normal (control) and MLKL knockout (KO) HeLa cells, using MLKL antibody (A13451) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
.jpg)
Immunohistochemistry of paraffin-embedded human liver cancer using MLKL Rabbit pAb (A13451) at dilution of 1:200 (40x lens).
.jpg)
Immunohistochemistry of paraffin-embedded human breast cancer using MLKL antibody (A13451) at dilution of 1:100 (40x lens).
[KO Validated] MLKL Rabbit pAb
Catalog No：AB-A13451
Manufacturer：ABclonal
Synonyms：MLKL;hMLKL
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €1.170,00
| Product Name: | [KO Validated] MLKL Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene. |
| Immunogen: | Recombinant protein of mouse MLKL |
| Gene ID: | 74568 |
| Swiss prot: | Q9D2Y4 |
| Molecular weight: | 53kDa/54kDa |
Help & Support
Product
Guarantee and
Expert Support
Related products
Catalog No：AB-A0987
Manufacturer：ABclonal
Synonyms：DJ-1;DJ1;GATD2;HEL-S-67p;PARK7
Applications：WB,IF
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €485,00
Catalog No：AB-A0962
Manufacturer：ABclonal
Synonyms：MGC:45012;TRAP;TRAP3;TRAF2
Applications：WB,IF,IP
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
Catalog No：AB-A0942
Manufacturer：ABclonal
Synonyms：ADPRT;ADPRT 1;ADPRT1;ARTD1;PARP;PARP-1;PPOL;pADPRT-1;PARP1;Cleaved PARP;PARP1
Applications：WB,IHC,IF,IP
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
Catalog No：AB-A0739
Manufacturer：ABclonal
Synonyms：NF2;ACN;BANF;SCH;merlin
Applications：WB,IF,IP
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
Catalog No：AB-A0229
Manufacturer：ABclonal
Synonyms：ERK;ERK-2;ERK2;ERT1;MAPK2;P42MAPK;PRKM1;PRKM2;p38;p40;p41;p41mapk;p42-MAPK;MAPK1
Applications：WB,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00
Catalog No：AB-A0207
Manufacturer：ABclonal
Synonyms：BCL2L4;BAX
Applications：WB,IHC,IF,IP
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €485,00