Western blot analysis of extracts of various cell lines, using TBL1XR1 antibody (A13438) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 10s.
TBL1XR1 Rabbit pAb
Catalog No:AB-A13438
Manufacturer:ABclonal
Synonyms:TBL1XR1;C21;DC42;IRA1;MRD41;TBLR1
Applications:WB,IF
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | TBL1XR1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human TBL1XR1 (NP_078941.2). |
Gene ID: | 79718 |
Swiss prot: | Q9BZK7 |
Molecular weight: | 55kDa |
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