Western blot analysis of extracts of mouse kidney, using C10orf2 antibody (A13433) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
C10orf2 Rabbit pAb
Catalog No:AB-A13433
Manufacturer:ABclonal
Synonyms:TWNK;ATXN8;C10orf2;IOSCA;MTDPS7;PEO;PEO1;PEOA3;PRLTS5;SANDO;SCA8;TWINL
Applications:WB
Reactivity:Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | C10orf2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5′ to 3′ direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 600 to the C-terminus of human C10orf2 (NP_068602.2). |
Gene ID: | 56652 |
Swiss prot: | Q96RR1 |
Molecular weight: | 60kDa/66kDa/77kDa |
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