Western blot analysis of extracts of various cell lines, using CHMP2B antibody (A13410) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 30s.
CHMP2B Rabbit pAb
Catalog No:AB-A13410
Manufacturer:ABclonal
Synonyms:CHMP2B;ALS17;CHMP2.5;DMT1;VPS2-2;VPS2B
Applications:WB,IHC,IF
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | CHMP2B Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-213 of human CHMP2B (NP_054762.2). |
Gene ID: | 25978 |
Swiss prot: | Q9UQN3 |
Molecular weight: | 19kDa/23kDa |
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