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Western blot analysis of extracts of various cell lines, using LRP6 antibody (A13325) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 90s.
LRP6 Rabbit pAb
Catalog No：AB-A13325
Manufacturer：ABclonal
Synonyms：LRP6;ADCAD2;STHAG7
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | LRP6 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-325 of human LRP6 (NP_002327.2). |
| Gene ID: | 4040 |
| Swiss prot: | O75581 |
| Molecular weight: | 180kDa |
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