Western blot analysis of extracts of mouse spleen, using DR1 antibody (A13298) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
DR1 Rabbit pAb
Catalog No:AB-A13298
Manufacturer:ABclonal
Synonyms:DR1;NC2;NC2-BETA;NC2B;NCB2
Applications:WB,IHC,IF
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | DR1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-176 of human DR1 (NP_001929.1). |
Gene ID: | 1810 |
Swiss prot: | Q01658 |
Molecular weight: | 19kDa |
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