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Western blot analysis of extracts of various cell lines, using USB1 antibody (A13229) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 180s.
USB1 Rabbit pAb
Catalog No：AB-A13229
Manufacturer：ABclonal
Synonyms：USB1;C16orf57;HVSL1;Mpn1;PN;hUsb1
Applications：WB
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | USB1 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a protein with several conserved domains, however, its exact function is not known. Mutations in this gene are associated with poikiloderma with neutropenia (PN), which shows phenotypic overlap with Rothmund-Thomson syndrome (RTS) caused by mutations in the RECQL4 gene. It is believed that this gene product interacts with RECQL4 protein via SMAD4 proteins, explaining the partial clinical overlap between PN and RTS. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-265 of human USB1 (NP_078874.2). |
| Gene ID: | 79650 |
| Swiss prot: | Q9BQ65 |
| Molecular weight: | 20kDa/28kDa/30kDa |
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