M40 acetate(143896-17-7 free base)
Catalog No:TA-TP1992L
Manufacturer:TargetMol
CAS No.:TP1992L
Formula:C96H149N23O26
MWt:2041.38
€217,00 – €5.013,00
Name: | M40 acetate(143896-17-7 free base) |
Category: | Biochemicals |
Description: | M40 acetate is a potent, non-selective galanin receptor antagonist (Ki values are 1.82 and 5.1 nM at GAL1 and GAL2 respectively) that inhibits galanin (1-29) binding in rat brain in vitro (IC50 = 3 – 15 nM). Attenuates the antidepressant effects of fluoxetine and blocks galanin-induced food intake in vivo. Also exhibits weak partial agonist activity at peripheral GAL2 receptors at doses > 100 nM. |
Pathway: | GPCR/G Protein,Neuroscience |
Target: | Neuropeptide Y Receptor |
Receptor: | galanin receptor |
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