ZIP acetate(863987-12-6 free base)
Catalog No：TA-TP1924L1
Manufacturer：TargetMol
CAS No.：TP1924L1
Formula：C92H158N30O19
MWt：1988.43
€149,00 – €3.056,00
| Name: | ZIP acetate(863987-12-6 free base) |
| Category: | Biochemicals |
| Description: | ZIP acetate is a novel, cell-permeable inhibitor of protein kinase Mζ (PKMζ), a constitutively active, atypical PKC isozyme involved in LTP maintenance. Selectively blocks PKMζ-induced synaptic potentiation in hippocampal slices in vitro. Reverses late-phase LTP (IC50 = 1 – 2.5 μM) and produces persistent loss of 1-day-old spatial memory following central administration in vivo. |
| Pathway: | Chromatin/Epigenetic,Cytoskeletal Signaling |
| Target: | PKC |
| Receptor: | PKC |
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