NoxA1ds acetate(1435893-78-9 free base)
Catalog No:TA-TP1886L1
Manufacturer:TargetMol
CAS No.:TP1886L1
Formula:C52H92N14O17
MWt:1185.35
€149,00 – €2.830,00
Name: | NoxA1ds acetate(1435893-78-9 free base) |
Category: | Biochemicals |
Description: | NoxA1ds acetate is a potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50 : 20 nM). Exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. Inhibits NOX1-derived O2- production in HT-29 human colon cancer cells. Attenuates VEGF-induced human pulmonary artery endothelial cell migration under hypoxic conditions in vitro. |
Pathway: | Immunology & Inflammation |
Target: | NADPH-oxidase |
Receptor: | NOX1 |
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