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Western blot analysis of extracts of various cell lines, using GDF5 antibody (A13167) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
GDF5 Rabbit pAb
Catalog No：AB-A13167
Manufacturer：ABclonal
Synonyms：GDF5;BDA1C;BMP-14;BMP14;CDMP1;LAP-4;LAP4;OS5;SYM1B;SYNS2
Applications：WB,IHC
Reactivity：Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | GDF5 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, multiple synostoses syndrome, proximal symphalangism, and susceptibility to osteoarthritis. |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human GDF5 (NP_000548.2). |
| Gene ID: | 8200 |
| Swiss prot: | P43026 |
| Molecular weight: | 55kDa |
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