2-Bromo-4'-hydroxyacetophenone [Cas No. 2491-38-5]
Catalog No:TA-T7084
Manufacturer:TargetMol
Synonyms:α-Bromo-4-hydroxyacetophenone,2-Bromo-4′-hydroxyacetophenone,4-Hydroxyphenacyl bromide,SHP-1 Inhibitor II
CAS No.:2491-38-5
Formula:C8H7BrO2
MWt:215.04
€20,00 – €55,00
Name: | PTP Inhibitor I |
Category: | Biochemicals |
Description: | PTP Inhibitor I is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2)) with a Ki value of 43 µM and PTP1B with a Ki value of 42 µM [1]. SHP-1 and PTP1B both have known roles in regulating insulin signaling as well as myeloid and lymphoid cell differentiation, making inhibitors of these phosphatases of interest in diabetes, cancer, allergy, and inflammation research [2]. |
Pathway: | Others |
Target: | phosphatase inhibitor |
Receptor: | PTP |
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