Valproic Acid [Cas No. 99-66-1]
Catalog No:TA-T7064
Manufacturer:TargetMol
Synonyms:2-Propylpentanoic Acid,VPA,2-Propylvaleric Acid,Sodium valproate,Depakine
CAS No.:99-66-1
Formula:C8H16O2
MWt:144.21
€20,00 – €59,00
Name: | Valproic Acid |
Category: | Biochemicals |
Description: | Valproic Acid is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels. Currently, the various molecular mechanisms of action of Valproic Acid have not been completely elucidated. Valproic Acid has been reported to be a potent inhibitor of histone deacetylases (HDACs) in vitro. Valproic Acid is also noted to relieve HDAC-dependent transcriptional repression and causes the hyperacetylation of histones in cultured cells. Additionally, Valproic Acid is reported to activate Wnt-dependent gene expression and to mimic trichostatin A (sc-3511) in the inhibition of histone deacetylase. |
Pathway: | Membrane transporter/Ion channel,NF-Κb,Chromatin/Epigenetic,DNA Damage/DNA Repair |
Target: | GABA Receptor activator,Sodium Channel inhibitor,HDAC |
Receptor: | GABA, Sodium Channel, HDACs,HDAC1 |
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