Rosmanol [Cas No. 80225-53-2]
Catalog No:TA-T7033
Manufacturer:TargetMol
CAS No.:80225-53-2
Formula:C20H26O5
MWt:346.42
€102,00 – €957,00
Name: | Rosmanol |
Category: | Biochemicals |
Description: | Rosmanol has antioxidant activity, it can activate the antioxidant response element. Rosmanol has biphasic modulation of GABAA receptors, demonstrates CNS activity in mouse models of antinociception, antidepressant and anxiolysis. Rosmanol potently induces apoptosis through both the mitochondrial apoptotic pathway and death receptor pathway in human colon adenocarcinoma COLO 205 cells. Rosmanol has anti-inflammatory activity, it potently inhibits lipopolysaccharide-induced iNOS and COX-2 expression through downregulating MAPK, NF-kappaB, STAT3 and C/EBP signaling pathways. |
Pathway: | Oxidation, Immunology & Inflammation |
Target: | Antioxidant, COX inhibitor |
Receptor: | Antioxidant, COX-2 |
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