Picropodophyllin [Cas No. 477-47-4]
Catalog No：TA-T6943
Manufacturer：TargetMol
Synonyms：PPP,AXL1717,Picropodophyllin (PPP),Picropodophyllotoxin
CAS No.：477-47-4
Formula：C22H22O8
MWt：414.41
€63,00 – €1.180,00
| Name: | Picropodophyllin |
| Category: | Biochemicals |
| Description: | Picropodophyllin (PPP) is a specific IGF-1R inhibitor (IC50: 1 nM). Picropodophyllin specifically inhibits the activity and downregulates the cellular expression of IGF1R without interfering with activities of other growth factor receptors, such as receptors for insulin, epidermal growth factor, platelet-derived growth factor, fibroblast growth factor and mast/stem cell growth factor (KIT). |
| Pathway: | Tyrosine Kinase/Adaptors |
| Target: | IGF-1R inhibitor |
| Receptor: | IGF-1R |
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