Necrosulfonamide [Cas No. 1360614-48-7]
Catalog No：TA-T6904
Manufacturer：TargetMol
Synonyms：(E)-Necrosulfonamide
CAS No.：1360614-48-7
Formula：C18H15N5O6S2
MWt：461.47
€52,00 – €943,00
| Name: | Necrosulfonamid |
| Category: | Biochemicals |
| Description: | Necrosulfonamide is an inhibitor of necroptosis. Blocks mixed lineage kinase domain-like protein (MLKL), a critical substrate of receptor-interacting serine-threonine kinase 3 (RIP3) during necrosis. Prevents MLKL-RIP1-RIP3 necrosome complex from interacting with downstream necrosis effectors. Binds and inhibits gasdermin D. Inhibits pyroptosis. |
| Pathway: | MAPK |
| Target: | MLK antagonist |
| Receptor: | necrosis(MLKL) |
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