WYE-354 [Cas No. 1062169-56-5]
Catalog No：TA-T6731
Manufacturer：TargetMol
Synonyms：WYE 354,WYE-354
CAS No.：1062169-56-5
Formula：C24H29N7O5
MWt：495.53
€35,00 – €426,00
| Name: | WYE354 |
| Category: | Biochemicals |
| Description: | WYE-354(IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It blocks mTORC2/P-AKT(S473) and mTORC1/P-S6K(T389), not P-AKT(T308). The selectivity for mTOR is higher than PI3Kα (>100-fold) and PI3Kγ (>500-fold). |
| Pathway: | PI3K/Akt/mTOR signaling |
| Target: | mTOR inhibitor,PI3K inhibitor |
| Receptor: | mTOR, PI3Kα, PI3Kγ |
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