Indoximod [Cas No. 110117-83-4]
Catalog No:TA-T6543
Manufacturer:TargetMol
Synonyms:1-Methyl-D-tryptophan,NLG-8189,Indoximod (NLG-8189)
CAS No.:110117-83-4
Formula:C12H14N2O2
MWt:218.25
€50,00
Name: | Indoximod |
Category: | Biochemicals |
Description: | Indoximod is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades the essential amino acid tryptophan, and may increase or maintain tryptophan levels important to T cell function. Tryptophan depletion is associated with immunosuppression involving T cell arrest and anergy. |
Pathway: | Metabolism |
Target: | IDO inhibitor |
Receptor: | IDO |
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