Fludarabine Phosphate [Cas No. 75607-67-9]
Catalog No:TA-T6501
Manufacturer:TargetMol
Synonyms:F-ara-A (NSC 312887) Phosphate,fludara Phosphate,F-ara-AMP,NSC 312887 Phosphate
CAS No.:75607-67-9
Formula:C10H13FN5O7P
MWt:365.21
€50,00 – €223,00
Name: | Fludarabine Phosphate |
Category: | Biochemicals |
Description: | Fludarabine Phosphate is the phosphate salt of a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activity. Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. This metabolite may inhibit DNA polymerase alpha, ribonucleotide reductase, and DNA primase, thereby interrupting DNA synthesis and inhibiting tumor cell growth. |
Pathway: | DNA Damage/DNA Repair |
Target: | DNA/RNA Synthesis inhibitor |
Receptor: | DNA polymerase α, DNA polymerase δ |
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