Dofetilide [Cas No. 115256-11-6]
Catalog No：TA-T6476
Manufacturer：TargetMol
Synonyms：UK 68789,UK-68798,Tikosyn
CAS No.：115256-11-6
Formula：C19H27N3O5S2
MWt：441.56
€50,00 – €561,00
| Name: | Dofetilide |
| Category: | Biochemicals |
| Description: | Dofetilide is a sulfonamide class III antiarrhythmic agent and potassium channel blocker. Dofetilide selectively blocks cardiac ion channels of the rapid component of the delayed rectifier potassium current Ikr. This antiarrhythmic agent prolongs cardiac action potential duration and effective refractory period due to delayed repolarization without affecting conduction velocity. This results in a normal sinus rhythm. Dofetilide is used in the treatment of atrial fibrillation and flutter. |
| Pathway: | Membrane transporter/Ion channel |
| Target: | Potassium Channel inhibitor |
| Receptor: | Potassium Channel |
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