Bafetinib [Cas No. 859212-16-1]
Catalog No：TA-T6311
Manufacturer：TargetMol
Synonyms：NS-187,INNO-406
CAS No.：859212-16-1
Formula：C30H31F3N8O
MWt：576.62
€31,00 – €531,00
| Name: | Bafetinib |
| Category: | Biochemicals |
| Description: | Bafetinib (INNO-406) is an effective and specific dual Bcr-Abl/Lyn inhibitor (IC50: 5.8/19 nM), and no inhibition of the phosphorylation of the T315I mutant and less effective to c-Kit and PDGFR. |
| Pathway: | Angiogenesis, Cytoskeletal Signaling,Tyrosine Kinase/Adaptors |
| Target: | Bcr-Abl inhibitor, Src inhibitor |
| Receptor: | Abl, Lyn |
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