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Western blot analysis of extracts of various cell lines, using SNX13 antibody (A12821) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
SNX13 Rabbit pAb
Catalog No：AB-A12821
Manufacturer：ABclonal
Synonyms：SNX13;RGS-PX1
Applications：WB,IF
Reactivity：Human,Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | SNX13 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-230 of human SNX13 (NP_055947.1). |
| Gene ID: | 23161 |
| Swiss prot: | Q9Y5W8 |
| Molecular weight: | 110kDa/112kDa |
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