URMC-099 [Cas No. 1229582-33-5]
Catalog No:TA-T6057
Manufacturer:TargetMol
Synonyms:URMC 099,URMC-099
CAS No.:1229582-33-5
Formula:C27H27N5
MWt:421.54
€54,00 – €449,00
Name: | URMC099 |
Category: | Biochemicals |
Description: | URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50: 19/42/14/150 nM, for MLK1/MLK2/MLK3/DLK), and also inhibits LRRK2 activity (IC50: 11 nM). |
Pathway: | Cell Cycle/Checkpoint,Angiogenesis,Autophagy,DNA Damage/DNA Repair,MAPK,Metabolism,Tyrosine Kinase/AdaptorsChromatin/EpigeneticCytoskeletal SignalingStem Cells |
Target: | Aurora Kinase inhibitor,Bcr-Abl inhibitor,CDK inhibitor,c-Met/HGFR inhibitor,DNA Alkylation inhibitor,IGF-1R inhibitor,LRRK2 inhibitor,MEK inhibitor,MLK |
Receptor: | Aurora A, Aurora B, Aurora C, Abl1, CDK1, CDK2, c-Met, DLK, IGF-1R, Insulin Receptor, LRRK2, MEKK2, MLK1, MLK2, MLK3, ROCK1, ROCK2, SGK, SGK1, Lck, Syk, TrkA, TrkB, VEGFR1/FLT1 |
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