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Western blot analysis of extracts of mouse skeletal muscle, using LIFR antibody (A12783) at 1:3000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 30s.
LIFR Rabbit pAb
Catalog No：AB-A12783
Manufacturer：ABclonal
Synonyms：LIFR;CD118;LIF-R;SJS2;STWS;SWS
Applications：WB
Reactivity：Mouse
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | LIFR Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human LIFR (NP_002301.1). |
| Gene ID: | 3977 |
| Swiss prot: | P42702 |
| Molecular weight: | 123kDa |
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