Western blot analysis of extracts of various cell lines, using JAG1 antibody (A12733) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 90s.
JAG1 Rabbit pAb
Catalog No:AB-A12733
Manufacturer:ABclonal
Synonyms:JAG1;AGS;AGS1;AHD;AWS;CD339;HJ1;JAGL1;jagged 1
Applications:WB,IF
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | JAG1 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 34-180 of human JAG1 (NP_000205.1). |
Gene ID: | 182 |
Swiss prot: | P78504 |
Molecular weight: | 116kDa/133kDa |
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