Rauwolscine hydrochloride [Cas No. 6211-32-1]
Catalog No:TA-T4429
Manufacturer:TargetMol
Synonyms:Corynanthidine hydrochloride,Isoyohimbine hydrochloride,α-Yohimbine hydrochloride
CAS No.:6211-32-1
Formula:C21H27ClN2O3
MWt:390.9
€50,00 – €112,00
Name: | Rauwolscine hydrochloride |
Category: | Biochemicals |
Description: | Rauwolscine, a natural alkaloid, is a specific and reversible α2-adrenergic receptor antagonist (Ki: 12 nM) [1]. It is a stereoisomer of yohimbine, which potently antagonizes both α1- and α2-adrenergic receptors [1]. Rauwolscine also acts as a receptor antagonist at the serotonin 5-HT2B receptor (Ki: 14.3 nM) and as a weak partial agonist at 5-HT1A (IC50: 1.3 μM) [3]. The α2-adrenergic receptor has diverse physiological functions and antagonists like rauwolscine have numerous applications, including the modulation of mood and behavior [5]. |
Pathway: | GPCR/G Protein,Neuroscience |
Target: | Adrenergic Receptor |
Receptor: | α2 adrenergic receptor |
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