Rauwolscine hydrochloride [Cas No. 6211-32-1]
Catalog No：TA-T4429
Manufacturer：TargetMol
Synonyms：Corynanthidine hydrochloride,Isoyohimbine hydrochloride,α-Yohimbine hydrochloride
CAS No.：6211-32-1
Formula：C21H27ClN2O3
MWt：390.9
€50,00 – €112,00
| Name: | Rauwolscine hydrochloride |
| Category: | Biochemicals |
| Description: | Rauwolscine, a natural alkaloid, is a specific and reversible α2-adrenergic receptor antagonist (Ki: 12 nM) [1]. It is a stereoisomer of yohimbine, which potently antagonizes both α1- and α2-adrenergic receptors [1]. Rauwolscine also acts as a receptor antagonist at the serotonin 5-HT2B receptor (Ki: 14.3 nM) and as a weak partial agonist at 5-HT1A (IC50: 1.3 μM) [3]. The α2-adrenergic receptor has diverse physiological functions and antagonists like rauwolscine have numerous applications, including the modulation of mood and behavior [5]. |
| Pathway: | GPCR/G Protein,Neuroscience |
| Target: | Adrenergic Receptor |
| Receptor: | α2 adrenergic receptor |
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