Betrixaban [Cas No. 330942-05-7]
Catalog No：TA-T4341
Manufacturer：TargetMol
Synonyms：PRT054021
CAS No.：330942-05-7
Formula：C23H22ClN5O3
MWt：451.91
€62,00 – €1.050,00
| Name: | Betrixaban |
| Category: | Biochemicals |
| Description: | Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity [3]. Betrixaban, now developed by Portola Pharmaceuticals Inc., is prescribed as a venous thromboembolism (VTE) prophylactic for adult patients with moderate to severe restricted motility or with other risks for VTE [2]. VTE can be manifested as deep vein thrombosis or pulmonary embolism and it is a leading cause of preventable death in hospitalized patients [4]. |
| Pathway: | Metabolism |
| Target: | Factor Xa |
| Receptor: | Factor Xa |
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