MICA Rabbit pAb
Catalog No:AB-A12622
Manufacturer:ABclonal
Synonyms:MICA;MIC-A;PERB11.1
Applications:WB,IHC
Reactivity:Human,Mouse
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | MICA Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-307 of human MICA (NP_000238.1). |
Gene ID: | 100507436 |
Swiss prot: | Q29983 |
Molecular weight: | 31kDa/42kDa |
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