CIL56 [Cas No. 300802-28-2]
Catalog No:TA-T4309
Manufacturer:TargetMol
Synonyms:CA3
CAS No.:300802-28-2
Formula:C23H27N3O5S2
MWt:489.6
€50,00 – €483,00
Name: | CIL56 |
Category: | Biochemicals |
Description: | CIL56 is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS). It also induces accumulation of long-chain saturated, monounsaturated, and polyunsaturated fatty acids in HT-1080 cells in vitro.HT-1080 cells lacking acetyl-CoA carboxylase 1 (ACC1), the rate-limiting enzyme in fatty acid synthesis, exhibit 5-fold resistance to CIL56 treatment, indicating ACC1 activity sensitizes cells to CIL56-induced cell death. |
Pathway: | Immunology & Inflammation |
Target: | ROS |
Receptor: | ROS |
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