(±)-Equol [Cas No. 94105-90-5]
Catalog No：TA-T4000
Manufacturer：TargetMol
Synonyms：Equol,(R,S)-Equol
CAS No.：94105-90-5
Formula：C15H14O3
MWt：242.3
€38,00 – €258,00
| Name: | (±)-Equol |
| Category: | Biochemicals |
| Description: | Equol is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzen by human intestinal microflora. The estrogen receptor (ER) agonist activity of the naturally occurring (S)-enantiomer (EC50 = 85 and 65 nM for human ERα and ERβ, respectively) is similar to that of genistein but exceeds that of daidzein. (S)-Equol preferentially binds ERβ (Ki = 0.73 nM) and demonstrates approximately 9-fold lower affinity for ERα (Ki = 6.41 nM). (S)-equol is also a potent antagonist of dihydrotestosterone, which has important implications for prostate cancer and other androgen-mediated pathologies. |
| Pathway: | Endocrinology/Hormones |
| Target: | Estrogen/progestogen Receptor agonist |
| Receptor: | ERα, ERβ |
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