Rhapontigenin [Cas No. 500-65-2]
Catalog No:TA-T3776
Manufacturer:TargetMol
Synonyms:Protigenin
CAS No.:500-65-2
Formula:C15H14O4
MWt:258.3
€37,00 – €672,00
Name: | Rhapontigenin |
Category: | Biochemicals |
Description: | Rhapontigenin is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer activity. At higher concentrations, rhapontigenin inhibits the proliferation of HL-60R and HepG2 cancer cell lines (IC50: 48 μM). |
Pathway: | Metabolism |
Target: | P450 inhibitor |
Receptor: | CYP1A1 |
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