TTR Rabbit pAb
Catalog No：AB-A12526
Manufacturer：ABclonal
Synonyms：TTR;CTS;CTS1;HEL111;HsT2651;PALB;TBPA
Applications：WB,IF
Reactivity：Human,Rat
Host：Rabbit
Conjugate：No
€65,00 – €325,00
| Product Name: | TTR Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-147 of human TTR (NP_000362.1). |
| Gene ID: | 7276 |
| Swiss prot: | P02766 |
| Molecular weight: | 15kDa |
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