GSK180736A [Cas No. 817194-38-0]
Catalog No:TA-T3513
Manufacturer:TargetMol
Synonyms:GSK180736
CAS No.:817194-38-0
Formula:C19H16FN5O2
MWt:365.13
€59,00 – €663,00
Name: | GSK180736A |
Category: | Biochemicals |
Description: | GSK180736A is an effective and selective GRK2 inhibitor (IC50: 0.77 μM) and >100-fold selectivity over other GRKs. It is a weak inhibitor of PKA (IC50: 30 μM), but highly effective against ROCK1 (IC50: 100 nM). |
Pathway: | Cell Cycle/Checkpoint, GPCR/G Protein, Stem Cells, Cytoskeletal Signaling |
Target: | GRK inhibitor, PKA inhibitor, ROCK inhibitor |
Receptor: | GRK1, GRK2, GRK5, PKA, ROCK |
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