MK-571 sodium [Cas No. 115103-85-0]
Catalog No:TA-T3148
Manufacturer:TargetMol
Synonyms:L-660711 (sodium salt),MK-571 sodium salt,MK571,L-660711,Verlukast sodium,L-660711 sodium salt
CAS No.:115103-85-0
Formula:C26H27ClN2O3S2﹞Na
MWt:537.07
€60,00 – €739,00
Name: | Propanoic acid |
Category: | Biochemicals |
Description: | MK-571 is a selective, orally active antagonist of the CysLT1 receptor. MK571 is a multidrug resistance protein-2 (ABCC2, Mrp2) inhibitor used to demonstrate the role of Mrp2 in the cellular efflux of drugs, xenobiotics, and their conjugates. MK571 can inhibit the synthesis of K-4′-O-GlcA (19.7 μM). MK571 dose-dependently inhibits the intracellular biosynthesis of all flavonol sulphates and glucuronides by Caco-2 cells. MK571 significantly inhibits phase-2 conjugation of kaempferol by cell-free extracts of Caco-2, and production of kaempferol-4′-O-glucuronide was competitively inhibited. In addition to inhibiting MRP2, MK571 is a potent inhibitor of enterocyte phase-2 conjugation. |
Pathway: | Immunology & Inflammation |
Target: | LTR antagonist |
Receptor: | CysLTR1 |
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