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Western blot analysis of extracts of various cell lines, using PPP1CA antibody (A12468) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).
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Immunohistochemistry of paraffin-embedded human liver cancer using PPP1CA antibody (A12468) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human esophagus using PPP1CA antibody (A12468) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human esophageal cancer using PPP1CA antibody (A12468) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse brain using PPP1CA antibody (A12468) at dilution of 1:100 (40x lens).
PPP1CA Rabbit pAb
Catalog No：AB-A12468
Manufacturer：ABclonal
Synonyms：PPP1CA;PP-1A;PP1A;PP1alpha;PPP1A
Applications：WB,IHC
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | PPP1CA Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of human PPP1CA (NP_002699.1). |
| Gene ID: | 5499 |
| Swiss prot: | P62136 |
| Molecular weight: | 32kDa/37kDa/38kDa |
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