IL13 Rabbit pAb
Catalog No:AB-A12460
Manufacturer:ABclonal
Synonyms:IL13;IL-13;P600
Applications:WB
Reactivity:Rat
Host:Rabbit
Conjugate:No
€65,00 – €325,00
Product Name: | IL13 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-146 of human IL13 (NP_002179.2). |
Gene ID: | 3596 |
Swiss prot: | P35225 |
Molecular weight: | 15kDa |
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