Bromfenac sodium hydrate [Cas No. 120638-55-3]
Catalog No：TA-T2403
Manufacturer：TargetMol
Synonyms：Bromfenac monosodium salt sesquihydrate,Bromfenac sodium hydrate
CAS No.：120638-55-3
Formula：C15H12BrNO3﹞3/2H2O﹞Na
MWt：383.17
€46,00 – €453,00
| Name: | Bromfenac sodium |
| Category: | Biochemicals |
| Description: | Bromfenac Sodium is the sodium salt form of bromfenac, a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and anti-inflammatory activities. Upon ophthalmic administration, bromfenac binds to and inhibits the activity of cyclooxygenase II (COX II), an enzyme which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins (PG). By inhibiting PG formation, bromfenac is able to inhibit PG-induced inflammation, thereby preventing vasodilation, leukocytosis, disruption of the blood-aqueous humor barrier, an increase in vascular permeability and an increase in intraocular pressure (IOP). |
| Pathway: | Immunology & Inflammation, Neuroscience |
| Target: | COX inhibitor |
| Receptor: | COX-2 |
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