Western blot analysis of extracts of HepG2 cells, using F2 antibody (A12382) at 1:500 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 180s.
F2 Rabbit pAb
Catalog No:AB-A12382
Manufacturer:ABclonal
Synonyms:F2;PT;RPRGL2;THPH1
Applications:WB,IF
Reactivity:Human,Mouse,Rat
Host:Rabbit
Conjugate:No
€65,00 – €370,00
Product Name: | F2 Rabbit pAb |
Category: | Polyclonal Antibodies |
Description: | Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 75-280 of human F2 (NP_000497.1). |
Gene ID: | 2147 |
Swiss prot: | P00734 |
Molecular weight: | 70kDa |
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