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Western blot analysis of extracts of Jurkat cells, using DR5/TRAILR2/TNFRSF10B antibody (A1236) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.
DR5/TRAILR2/TNFRSF10B Rabbit pAb
Catalog No：AB-A1236
Manufacturer：ABclonal
Synonyms：CD262;DR5;KILLER;KILLER/DR5;TRAIL-R2;TRAILR2;TRICK2;TRICK2A;TRICK2B;TRICKB;ZTNFR9;TNFRSF10B
Applications：WB
Reactivity：Human
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | DR5/TRAILR2/TNFRSF10B Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 56-210 of human DR5/TRAILR2/TNFRSF10B (NP_003833.4). |
| Gene ID: | 8795 |
| Swiss prot: | O14763 |
| Molecular weight: | 12kDa/45kDa/47kDa |
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