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Western blot analysis of extracts of rat heart, using MYBPC3 antibody (A12351) at 1:3000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 1s.
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Immunohistochemistry of paraffin-embedded rat heart using MYBPC3 antibody (A12351) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse heart using MYBPC3 antibody (A12351) at dilution of 1:100 (40x lens).
MYBPC3 Rabbit pAb
Catalog No：AB-A12351
Manufacturer：ABclonal
Synonyms：MYBPC3;CMD1MM;CMH4;FHC;LVNC10;MYBP-C;cardiac
Applications：WB,IHC
Reactivity：Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | MYBPC3 Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 200-400 of human MYBPC3 (NP_000247.2). |
| Gene ID: | 4607 |
| Swiss prot: | Q14896 |
| Molecular weight: | 140kDa |
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