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Western blot analysis of extracts of various cell lines, using PGC1α antibody (A12348) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 180s.
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Immunohistochemistry of paraffin-embedded mouse heart using PGC1α Rabbit pAb (A12348) at dilution of 1:50 (40x lens).
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Immunohistochemistry of paraffin-embedded rat kidney using PGC1α Rabbit pAb (A12348) at dilution of 1:50 (40x lens).
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Immunohistochemistry of paraffin-embedded rat liver using PGC1α Rabbit pAb (A12348) at dilution of 1:50 (40x lens).
PGC1α Rabbit pAb
Catalog No：AB-A12348
Manufacturer：ABclonal
Synonyms：PPARGC1A;LEM6;PGC-1(alpha);PGC-1alpha;PGC-1v;PGC1;PGC1A;PPARGC1;PPARG coactivator 1 alpha;PGC1 alpha
Applications：WB,IHC,IF
Reactivity：Human,Mouse,Rat
Host：Rabbit
Conjugate：No
€65,00 – €370,00
| Product Name: | PGC1α Rabbit pAb |
| Category: | Polyclonal Antibodies |
| Description: | The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 700 to the C-terminus of human PGC1α (NP_037393.1). |
| Gene ID: | 10891 |
| Swiss prot: | Q9UBK2 |
| Molecular weight: | 14kDa/30kDa/31kDa/33kDa/77kDa/89kDa/91kDa |
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