Western blot analysis of extracts of various cell lines, using Ku80 Rabbit mAb (A12338) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit (RM00020).|Exposure time: 5s.
Ku80 Rabbit mAb
Catalog No:AB-A12338
Manufacturer:ABclonal
Synonyms:KARP-1, KARP1, KU80, KUB2, Ku86, NFIV
Applications:WB,IHC,IF
Reactivity:Human
Host:Rabbit
Conjugate:No
€65,00 – €485,00
Product Name: | Ku80 Rabbit mAb |
Category: | Monoclonal Antibodies |
Description: | The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008] |
Immunogen: | A synthesized peptide derived from human Ku80 |
Gene ID: | 7520 |
Swiss prot: | P13010 |
Molecular weight: | 83kDa |
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