Suramin Sodium Salt [Cas No. 129-46-4]
Catalog No：TA-T2160
Manufacturer：TargetMol
Synonyms：BAY-205,NF-060,Suramin hexasodium salt
CAS No.：129-46-4
Formula：C51H34N6Na6O23S6
MWt：1429.15
€41,00 – €554,00
| Name: | Suramin Sodium Salt |
| Category: | Biochemicals |
| Description: | Suramin Sodium is a sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth factor I (IGF-I), epidermal growth factor (EGF), platelet-derived growth factor (PDGF), and tumor growth factor-beta (TGF-beta), to their receptors, thereby inhibiting endothelial cell proliferation and migration. This agent also inhibits vascular endothelial growth factor (VEGF)- and basic fibroblast growth factor (bFGF)-induced angiogenesis, retroviral reverse transcriptase, uncoupling of G-proteins from receptors, topoisomerases, cellular folate transport, and steroidogenesis. |
| Pathway: | DNA Damage/DNA Repair |
| Target: | Topoisomerase inhibitor |
| Receptor: | Topo II |
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