WP1066 [Cas No. 857064-38-1]
Catalog No:TA-T2156
Manufacturer:TargetMol
CAS No.:857064-38-1
Formula:C17H14BrN3O
MWt:356.22
€48,00 – €768,00
Name: | WP1066 |
Category: | Biochemicals |
Description: | WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells, shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3. WP1066 has been used in trials studying the treatment of Melanoma, Brain Cancer, Solid Tumors, and Central Nervous System Neoplasms. |
Pathway: | Angiogenesis, JAK/STAT signaling, Chromatin/Epigenetic, Stem Cells |
Target: | JAK inhibitor, STAT inhibitor |
Receptor: | JAK2, STAT3 |
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